Thermo Fisher Scientific HVCN1 Polyclonal Antibody
HVCN1 단백질을 인식하는 Thermo Fisher Scientific의 Rabbit Polyclonal Antibody. Western blot, ICC/IF, Flow Cytometry 등 다양한 응용에 사용 가능. 동결건조 형태로 제공되며 -20°C 보관. 면역세포의 프로톤 채널 연구용으로 적합.
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Applications
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:200 |
| Immunocytochemistry (ICC/IF) | Assay-dependent |
| Flow Cytometry (Flow) | 1:25 |
Product Specifications
| Specification | Description |
|---|---|
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Peptide (C)GDDYHTWNVNYKK, corresponding to amino acid residues 32–44 of mouse HVCN1 |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | 0.8 mg/mL |
| Storage Conditions | -20°C |
| Shipping Conditions | Wet ice |
| RRID | AB_2735943 |
Product Specific Information
Product is shipped at room temperature as a lyophilized powder and should be stored at -20°C upon receipt.
Reconstitution: add 50 µL of deionized water.
Target Information
HVCN1 (hydrogen voltage-gated channel 1) is a voltage-gated proton channel protein highly expressed in immune tissues.
It mediates proton conductance required by phagocytic leukocytes for oxidative burst and microbial killing.
HVCN1 moderates voltage-dependent proton permeability by allowing proton flow according to electrochemical gradient.
It is sensitive to zinc ions and can be inhibited by them.
HVCN1 may represent a potential therapeutic target for B cell malignancies involving continued signaling via the B cell antigen receptor.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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