Thermo Fisher Scientific HLA-ABC Monoclonal Antibody (ICO-53)

Applications

Tested Dilution

Publications

Immunohistochemistry (IHC)

1:1,000

-

Flow Cytometry (Flow)

1:1,000

-

Product Specifications

Species Reactivity

Human

Host/Isotype

Mouse / IgG2a

Class

Monoclonal

Type

Antibody

Clone

ICO-53

Immunogen

HLA-ABC on all Leukocytes. if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:HLA-ABC,uniProtId:P04439-1,ncbiNodeId:9606,antigenRange:1-365,antigenLength:365,antigenImageFileName:MA1-7660_HLA-ABC_P04439-1_House_mouse.svg,antigenImageFileNamePDP:MA1-7660_HLA-ABC_P04439-1_House_mouse_PDP.jpeg,sortOrder:1},{targetFamily:HLA-ABC,uniProtId:P01889-1,ncbiNodeId:9606,antigenRange:1-362,antigenLength:362,antigenImageFileName:MA1-7660_HLA-ABC_P01889-1_House_mouse.svg,antigenImageFileNamePDP:MA1-7660_HLA-ABC_P01889-1_House_mouse_PDP.jpeg,sortOrder:2},{targetFamily:HLA-ABC,uniProtId:P10321-1,ncbiNodeId:9606,antigenRange:1-366,antigenLength:366,antigenImageFileName:MA1-7660_HLA-ABC_P10321-1_House_mouse.svg,antigenImageFileNamePDP:MA1-7660_HLA-ABC_P10321-1_House_mouse_PDP.jpeg,sortOrder:3}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

View immunogen .st0{fill:#FFFFFF;} .st1{fill:#1E8AE7;}

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

1 mg/mL

Purification

Protein A

Storage buffer

PBS, pH 7.2

Contains

0.01% sodium azide

Storage conditions

4°C short term, -80°C long term

RRID

AB_1076706

Product Specific Information

MA1-7660 detects HLA-ABC from human samples.

MA1-7660 has been successfully used in flow cytometry and Immunohistochemistry procedures.

The MA1-7660 immunogen is a HLA-ABC protein on all Leukocytes.

Target Information

HLA-class I major histocompatibility (MHC) antigens are intrinsic membrane glycoproteins expressed on nucleated cells and noncovalently associated with an invariant beta2 microglobulin. They carry foreign determinants important for immune recognition by cytotoxic T cells, thus important for anti-viral and anti-tumor defense. Human HLA-class I antigens are represented by HLA-A, HLA-B and HLA-C molecules.

HLA and MHC antibodies play a significant role in Immunopeptidomics, facilitating the identification and characterization of neoantigens through high-performance liquid chromatography coupled to tandem Mass Spectrometry.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.