Thermo Fisher Scientific HLA-ABC Monoclonal Antibody (ICO-53)
인간 HLA-ABC 항원을 인식하는 마우스 단클론 항체로, Flow Cytometry와 IHC에 최적화되어 있습니다. Protein A로 정제된 액상 형태이며, 면역펩티도믹스 연구 및 항바이러스·항종양 방어 기전 연구에 활용됩니다.
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Thermo Fisher Scientific HLA-ABC Monoclonal Antibody (ICO-53)
Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Immunohistochemistry (IHC) | 1:1,000 |
| Flow Cytometry (Flow) | 1:1,000 |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG2a |
| Class | Monoclonal |
| Type | Antibody |
| Clone | ICO-53 |
| Immunogen | HLA-ABC on all Leukocytes |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein A |
| Storage Buffer | PBS, pH 7.2 |
| Contains | 0.01% sodium azide |
| Storage Conditions | 4°C short term, -80°C long term |
| RRID | AB_1076706 |
Product Specific Information
- MA1-7660 detects HLA-ABC from human samples.
- Successfully used in Flow Cytometry and Immunohistochemistry procedures.
- Immunogen is HLA-ABC protein expressed on all leukocytes.
Target Information
HLA-class I major histocompatibility (MHC) antigens are intrinsic membrane glycoproteins expressed on nucleated cells and associated with beta2 microglobulin.
They present foreign determinants for recognition by cytotoxic T cells, playing a critical role in antiviral and antitumor defense.
Human HLA-class I antigens include HLA-A, HLA-B, and HLA-C molecules.
HLA and MHC antibodies are essential in Immunopeptidomics, aiding in the identification and characterization of neoantigens through LC-MS/MS analysis.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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