Thermo Fisher Scientific TRAF6 Polyclonal Antibody
TRAF6 단백질을 인식하는 Rabbit Polyclonal 항체로, Western blot 및 Immunoprecipitation에 사용 가능. Human TRAF6의 472–522 아미노산 영역을 면역원으로 제작. 1 mg/mL 액상 형태로 제공되며 4°C에서 보관. 연구용으로만 사용 가능.
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Applications
| Application | Tested Dilution | Notes |
|---|---|---|
| Western Blot (WB) | 1:2,000–1:10,000 | |
| Immunoprecipitation (IP) | Assay-dependent |
Product Specifications
| 항목 | 내용 |
|---|---|
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Region between residue 472 and 522 of Human TNF Receptor-Associated Factor 6 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Storage Conditions | 4°C |
| Shipping Conditions | Wet ice |
Product Specific Information
The recommended shelf life for this product is 1 year from date of receipt.
Target Information
Tumor necrosis factor (TNF) receptor associated factors (TRAFs) were initially discovered as adaptor proteins linking the TNF receptor superfamily to signaling pathways, playing key roles in regulating cell death and stress responses.
TRAF proteins share a conserved region that mediates interactions with receptors and other TRAFs, activating various signaling cascades depending on the TRAFs involved.
For example, TRAF2 and TRAF3 bind to CD40, a member of the NF receptor superfamily, and are essential for NF-κB activation in mouse B lymphocytes. TRAF2, together with TRAF6, is required for CD40 signaling in non-hematopoietic cells. TRAF2 also interacts with the lymphotoxin-beta receptor (LTβR) along with TRAF3 and apoptosis inhibitors cIAP1 and Smac.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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