Thermo Fisher Scientific PD-L1 VHH-8His-Cys-tag Recombinant Alpaca Monoclonal Antibody (C3)
PD-L1 단백질을 표적으로 하는 알파카 유래 재조합 단일클론 항체입니다. ELISA 및 기능적 분석에 사용 가능하며, CHO 세포에서 발현되었습니다. Metal-chelate chromatography로 정제된 고순도 항체로, 1 mg/mL 농도의 액상 형태입니다. 연구용으로만 사용됩니다.
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Applications
ELISA (ELISA)
- Assay-dependent
Functional Assay (Functional)
- Assay-dependent
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Mouse |
| Host / Isotype | Alpaca / VHH |
| Expression System | CHO cells |
| Class | Recombinant Monoclonal |
| Type | Antibody |
| Clone | C3 |
| Immunogen | Recombinant Mouse CD274/PD-L1/B7-H1 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Metal-chelate chromatography |
| Storage Buffer | PBS |
| Contains | No preservative |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
Product Specific Information
- Compatible with Direct ELISA
Target Information
Programmed death receptor ligand 1 (PD-L1, also called B7-H1) is a recently described B7 family member. One specific receptor, programmed death receptor 1 (PD-1), can be ligated by PD-L1 and negatively regulates T-cell receptor (TCR) signaling. Upon receptor binding, PD-L1 decreases TCR-mediated proliferation and cytokine production. PD-L1 expression is abundant on many murine and human cancers and can be up-regulated upon IFN-gamma stimulation. Thus, PD-L1 may play an important role in tumor immune evasion.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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