Thermo Fisher Scientific K Cadherin Polyclonal Antibody
Thermo Fisher Scientific의 K Cadherin Polyclonal Antibody는 인간 K-cadherin을 인식하는 토끼 유래 IgG 항체입니다. Western blot, Flow cytometry, ELISA에 적용 가능하며, 고순도의 Protein A 정제 및 안정적인 액상 형태로 제공됩니다. 연구용으로만 사용됩니다.
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Applications
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:2,000 |
| Flow Cytometry (Flow) | 1:100 |
| ELISA | 1:500–1:1,000 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | KLH conjugated synthetic peptide derived from human K Cadherin (amino acids 281–380) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein A |
| Storage Buffer | 0.01M TBS, pH 7.4, with 1% BSA, 50% glycerol |
| Contains | 0.02% ProClin 300 |
| Storage Conditions | -20°C |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
Cadherins are transmembrane glycoproteins involved in Ca²⁺-dependent cell-cell interactions. Members of this family are differentially expressed in various tissues and play roles in tissue integrity and morphogenesis.
Cadherins are divided into type I and type II subgroups:
- Type I cadherins: E-cadherin (cadherin-1), N-cadherin (cadherin-2), P-cadherin (cadherin-3), R-cadherin (cadherin-4)
- Type II cadherins: K-cadherin (cadherin-6), OB-cadherin (cadherin-11)
Cadherin-6 is expressed in the proximal tubule epithelium of the kidney, from which most renal cell carcinomas are derived.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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