Thermo Fisher Scientific p75NTR Polyclonal Antibody
Thermo Fisher Scientific의 p75NTR Polyclonal Antibody는 마우스와 랫트 시료에 반응하며, Western blot 및 IHC에 적합합니다. 신경영양인자 수용체 p75 검출에 유용하며, 신경계 발달 및 손상 연구에 활용됩니다. 동결건조 형태로 제공되며 장기 안정성을 위해 -20°C 보관을 권장합니다.
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Applications and Tested Dilutions
| Application | Tested Dilution | Publications |
|---|---|---|
| Western Blot (WB) | 1:300–1:2,000 | - |
| Immunohistochemistry (IHC) | 1:300–1:2,000 | - |
| Miscellaneous PubMed (Misc) | - | View 3 publications |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Mouse, Rat |
| Published Species | Not Applicable |
| Host/Isotype | Rabbit / Ig |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthetic peptide from the cytoplasmic domain of rat p75NTR conjugated to an immunogenic carrier protein |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | Not determined |
| Storage Buffer | Whole serum |
| Contains | No preservative |
| Storage Conditions | Store at 4°C for short term. For long-term storage, store at -20°C, avoiding freeze/thaw cycles. Glycerol (1:1) may be added for added stability. |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
- Reconstitute in 100 µL of sterile water.
- Centrifuge to remove any insoluble material.
- The antigen is homologous in mouse.
- Specificity: p75NTR.
Target Information
Neurotrophic factors regulate the survival, differentiation, and maintenance of neurons in both peripheral and central nervous systems, as well as other neural crest-derived cell types. Developing sympathetic neurons depend on nerve growth factor (NGF) during target competition in vivo.
Antibodies specific to NGFR p75 are valuable tools for detecting and characterizing NGFR p75, aiding research into neural development, plasticity, and repair mechanisms.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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