Thermo Fisher Scientific CHD1L Polyclonal Antibody
Rabbit에서 유래한 CHD1L 폴리클로날 항체로, 인간 CHD1L 재조합 단백질을 면역원으로 제작되었습니다. 비결합형 액상 제품이며, 단기 보관은 4°C, 장기 보관은 -20°C에서 권장됩니다. DNA 손상 후 크로마틴 완화 연구에 적합합니다.
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Product Specifications
| 항목 | 내용 |
|---|---|
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant protein corresponding to Human CHD1L |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.1 mg/mL |
| Storage conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping conditions | Wet ice |
| RRID | AB_2639755 |
Product Specific Information
Immunogen sequence:
AWWESNNYQS FCLPSEESEP EDLENGEESS AELDYQDPDA TSLKYVSGDV THPQAGAEDA LIVHCVDDSG HWGRGGLFTA LEKRSAEPR
Antigen sequence identity:
- Mouse: 82%
- Rat: 80%
Target Information
In response to DNA strand breaks, chromatin adopts a relaxed structure due to the addition of poly(ADP-ribose) (PAR) to chromatin proteins by PARP enzymes (see PARP1; MIM 173870), and this relaxation facilitates the repair of DNA damage. CHD1L interacts with PAR and has a role in chromatin relaxation following DNA damage (Ahel et al., 2009 [PubMed 19661379]).
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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