Thermo Fisher Scientific MMP28 Polyclonal Antibody
MMP28 단백질을 인식하는 Rabbit Polyclonal Antibody로, WB, IHC(P), ICC/IF에 적합합니다. 인간, 마우스, 랫트 반응성을 가지며, Affinity chromatography로 정제되었습니다. PBS buffer에 50% glycerol 포함, -20°C 보관.
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- PA5100157
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- pk
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Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:2,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:50–1:200 |
| Immunocytochemistry (ICC/IF) | 1:100–1:500 |
Product Specifications
| Item | Description |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthesized peptide derived from human MMP28 (Accession Q9H239), corresponding to amino acid residues V291–I341. |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.4, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C |
| Shipping Conditions | Wet ice |
| RRID | AB_2815687 |
Product Specific Information
Antibody detects endogenous levels of total MMP28.
Target Information
Epilysin, also known as matrix metalloproteinase-28 (MMP-28), is a secreted protein belonging to the peptidase M10A family. Matrix metalloproteinases are responsible for extracellular matrix breakdown, which is essential for physiological processes such as tissue remodeling, reproduction, and embryonic development.
Epilysin is produced by proliferating keratinocytes and mediates the degradation of casein. Its expression increases in response to skin injury, suggesting a role in tissue repair and homeostasis. Additionally, Epilysin may function in the nervous system; incubation with rat embryonic brain tissue results in degradation of myelin proteins. In Xenopus, Epilysin localizes to nerves and is upregulated during neurulation, indicating an evolutionarily conserved role in neural development and modulation of the axonal-glial extracellular environment.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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