Thermo Fisher Scientific RBFOX2 Monoclonal Antibody (1E7G10)
RBFOX2 단백질을 인식하는 Mouse IgG1 단클론 항체로, Western blot, IHC, Flow cytometry, ELISA에 사용 가능. 인간 시료에 반응하며, Protein G 정제 및 PBS buffer에 보관. 연구용으로 RNA 결합 단백질 분석에 적합.
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Thermo Fisher Scientific RBFOX2 Monoclonal Antibody (1E7G10)
Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:2,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:200–1:1,000 |
| Flow Cytometry (Flow) | 1:200–1:400 |
| ELISA | 1:10,000 |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | 1E7G10 |
| Immunogen | Purified recombinant fragment of human RBFOX2 (aa 1–145) expressed in E. coli |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein G |
| Storage Buffer | PBS |
| Contains | 0.05% sodium azide |
| Storage Conditions | Store at 4°C for short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2898535 |
Product Specific Information
This antibody has been tested in indirect ELISA.
Target Information
The RBFOX2 gene encodes an RNA binding protein that regulates alternative exon splicing in the nervous system and other cell types. It binds to the conserved UGCAUG element downstream of many alternatively spliced exons, promoting inclusion of the alternative exon in mature transcripts. RBFOX2 also interacts with the estrogen receptor 1 transcription factor, influencing its transcriptional activity. Multiple transcript variants encoding different isoforms are known.
For Research Use Only.
Not for use in diagnostic procedures. Not for resale without express authorization.
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