Thermo Fisher Scientific Diazepam Binding Inhibitor Monoclonal Antibody (20B10)
Diazepam Binding Inhibitor 단백질을 인식하는 Mouse IgG1 단일클론 항체. ELISA 및 IP에 사용 가능. HepG2 세포를 양성 대조군으로 권장. 연구용으로만 사용, 인체 진단용 불가.
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Thermo Fisher Scientific Diazepam Binding Inhibitor Monoclonal Antibody (20B10)
Applications
- ELISA (ELISA): Assay-dependent
- Immunoprecipitation (IP): 1–2 µL
Product Specifications
| 항목 | 내용 |
|---|---|
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | 20B10 |
| Immunogen | Purified, recombinant, human, GST-fusion protein expressed in E. coli |
| Conjugate | Unconjugated |
| Form | Liquid |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Wet ice |
| RRID | AB_2089478 |
Product Specific Information
A suggested positive control for this product is HepG2 cells.
Target Information
Diazepam binding inhibitor (DBI) is a hormone-regulated protein involved in lipid metabolism and the displacement of beta-carbolines and benzodiazepines, which modulate signal transduction at type A GABA receptors in brain synapses.
It is conserved from yeast to mammals, with a highly conserved hydrophobic domain of seven residues forming the binding site for medium- and long-chain acyl-CoA esters.
DBI mediates feedback regulation of pancreatic secretion and postprandial release of cholecystokinin, and acts as a mediator in corticotropin-dependent adrenal steroidogenesis.
Three pseudogenes have been identified on chromosomes 6, 8, and 16. Multiple transcript variants encoding different isoforms are described.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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