Thermo Fisher Scientific SHMT1 Polyclonal Antibody
인간 SHMT1 단백질을 인식하는 Rabbit Polyclonal 항체. Western blot, IHC, ICC/IF에 적합하며 항원 친화 크로마토그래피로 정제됨. PBS 기반 완충액에 보관되며 연구용으로만 사용 가능.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 0.04–0.4 µg/mL |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:500–1:1,000 |
| Immunocytochemistry (ICC/IF) | 0.25–2 µg/mL |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant protein corresponding to Human SHMT1. Recombinant protein control fragment (Product #RP-93454). |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.2, with 40% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2647280 |
Product Specific Information
Immunogen sequence:
MTMPVNGAHK DADLWSSHDK MLAQPLKDSD VEVYNIIKKE SNRQRVGLEL IASENFASRA VLEALGSCL
Sequence identity to orthologs:
- Mouse: 78%
- Rat: 75%
Target Information
This gene encodes the cellular form of serine hydroxymethyltransferase, a pyridoxal phosphate-containing enzyme that catalyzes the reversible conversion of serine and tetrahydrofolate to glycine and 5,10-methylene tetrahydrofolate.
This reaction provides one-carbon units for synthesis of methionine, thymidylate, and purines in the cytoplasm.
The gene is located within the Smith-Magenis syndrome region on chromosome 17.
Alternative splicing results in two transcript variants encoding different isoforms. Additional variants have been described, but their biological validity has not been determined.
For Research Use Only.
Not for use in diagnostic procedures. Not for resale without express authorization.
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