Thermo Fisher Scientific HJURP Polyclonal Antibody
HJURP 단백질을 인식하는 Rabbit Polyclonal 항체로, Western blot 및 Immunoprecipitation에 적합합니다. 항원 친화 크로마토그래피로 정제되었으며, 1 mg/mL 농도의 액상 형태입니다. 인간 시료에 반응하며 연구용으로만 사용됩니다.
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Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:2,000–1:10,000 |
| Immunoprecipitation (IP) | 2–5 µg/mg lysate |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Region between residue 700 and 748 of human Holliday Junction Recognition Protein (HJURP) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | Phosphate/Tris citrate, pH 7–8 |
| Contains | 0.09% sodium azide |
| Storage Conditions | 4°C |
| Shipping Conditions | Wet ice |
Product Specific Information
The recommended shelf life for this product is 1 year from the date of receipt.
Target Information
Holliday Junction Recognition Protein (HJURP) is a centromeric protein that plays a key role in the incorporation and maintenance of the histone H3-like variant CENPA at centromeres.
It acts as a specific chaperone for CENPA, facilitating incorporation of newly synthesized CENPA into nucleosomes at replicated centromeres.
HJURP prevents CENPA-H4 tetramerization and premature DNA binding, and directly binds to Holliday junctions.
For Research Use Only.
Not for use in diagnostic procedures.
Not for resale without express authorization.
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