Thermo Fisher Scientific CYP7A1 Polyclonal Antibody
CYP7A1 단백질을 인식하는 Thermo Fisher Scientific의 폴리클로날 항체로, 인간·마우스·랫에서 반응합니다. Western blot, IHC, ICC/IF에 적합하며, 고순도 친화 크로마토그래피로 정제되었습니다. 액상 형태로 -20°C 보관하며 연구용으로만 사용됩니다.
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Applications and Tested Dilution
| Application | Tested Dilution | Publications |
|---|---|---|
| Western Blot (WB) | 1:500–1:2,000 | View 3 publications |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:50–1:200 | - |
| Immunocytochemistry (ICC/IF) | 1:100–1:500 | - |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Published Species | Human, Mouse |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthesized peptide derived from human CYP7A1 (Accession P22680), corresponding to amino acid residues K93–E143 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.4, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C |
| Shipping Conditions | Wet ice |
| RRID | AB_2850387 |
Product Specific Information
Antibody detects endogenous levels of total Cytochrome P450 7A1.
Target Information
CYP7A1 is a member of the cytochrome P450 superfamily of enzymes. These monooxygenases catalyze reactions involved in drug metabolism and synthesis of cholesterol, steroids, and other lipids. This endoplasmic reticulum membrane protein catalyzes the first reaction in the cholesterol catabolic pathway in the liver, converting cholesterol to bile acids. This reaction is the rate-limiting step and the major site of regulation of bile acid synthesis, which is the primary mechanism for cholesterol removal from the body.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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