Thermo Fisher Scientific CD215 (IL-15Ra) Polyclonal Antibody

Applications

Western Blot (WB)

• Tested Dilution: 1.0 µg/mL
• View 1 publication

Product Specifications

Product Specific Information

• Immunogen sequence: NYSVNSRERY VCNSGFKRKA GTSTLIECVI NKNTNVAHWT TPSLKCIRDP
• Short-term storage: 2–8°C (up to 1 week)
• Long-term storage: -20°C in small aliquots to prevent freeze-thaw cycles
• Predicted homology:
  • Cow: 100%
  • Dog: 100%
  • Guinea Pig: 100%
  • Horse: 100%
  • Human: 100%
  • Mouse: 92%
  • Rabbit: 100%
  • Rat: 100%

Target Information

Interleukin 15 (IL-15RA) is a cytokine receptor that binds IL-15 with high affinity. IL-15 regulates T and natural killer cell activation and proliferation. The IL-15 and IL-2 receptors share two subunits (IL-2Rβ and IL-2Rγ), and IL-15RA is structurally related to IL-2RA, an additional IL-2-specific alpha subunit necessary for high-affinity IL-2 binding. Unlike IL-2RA, IL-15RA binds IL-15 independently of other subunits and is thought to enhance cell proliferation and expression of apoptosis inhibitors Bcl-xL and Bcl-2.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.