Thermo Fisher Scientific GPM6A Polyclonal Antibody
GPM6A 단백질을 인식하는 Thermo Fisher Scientific의 Rabbit Polyclonal Antibody로, WB 및 IHC에 적합합니다. 인간 및 설치류 반응성을 가지며, 액상 형태로 제공됩니다. 신경세포 분화 및 시냅스 형성 연구에 활용 가능합니다.
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Applications
Western Blot (WB)
- Tested Dilution: 1:8,000
Immunohistochemistry (IHC)
- Tested Dilution: 1:1,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Rat |
| Host/Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide directed towards the middle region of human GPM6A (aa 226–275) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.5 mg/mL |
| Purification | Affinity chromatography |
| Storage buffer | PBS with 2% sucrose |
| Contains | 0.09% sodium azide |
| Storage conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping conditions | Wet ice |
| RRID | AB_2692247 |
Product Specific Information
This target displays homology in the following species:
Cow: 100%; Dog: 100%; Guinea Pig: 100%; Horse: 100%; Human: 100%; Mouse: 100%; Rabbit: 100%; Rat: 100%; Zebrafish: 100%
Target Information
Neuronal membrane glycoprotein M6-a is a protein encoded by the GPM6A gene in humans. It is involved in neuronal differentiation, including differentiation and migration of neuronal stem cells. Plays a role in neuronal plasticity, neurite and filopodia outgrowth, filopodia motility, and possibly synapse formation.
GPM6A-induced filopodia formation involves MAPK and Src signaling pathways. May participate in NGF-dependent Ca²⁺ influx, and the regulation of endocytosis and intracellular trafficking of GPCRs; enhances internalization and recycling of mu-type opioid receptor.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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