Thermo Fisher Scientific ITGA3 Polyclonal Antibody
ITGA3 단백질을 인식하는 Rabbit Polyclonal Antibody로, WB, IHC, ICC/IF에 적합합니다. Human, Mouse, Rat, Non-human primate 반응성을 가지며, Affinity chromatography로 정제되었습니다. PBS/glycerol buffer에 보관하며 -20°C에서 안정적으로 저장 가능합니다.
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Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:2,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:50–1:200 |
| Immunocytochemistry (ICC/IF) | 1:100–1:500 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Non-human primate, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthesized peptide derived from human ITGA3 (Accession P26006), corresponding to amino acid residues C496–P546. Target family: CD49c (Integrin alpha 3), UniProt ID: P26006-2, Antigen range: 496–546 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.4, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C |
| Shipping Conditions | Wet ice |
| RRID | AB_2818340 |
Product Specific Information
Antibody detects endogenous levels of total Integrin alpha 3.
Target Information
ITGA3 (INTEGRIN, ALPHA-3), also known as CD49C, VLA3, or GAPB3, is a member of the integrin alpha subunit family and functions as a cell surface adhesion molecule.
It is encoded by the ITGA3 gene located on chromosome 17q21.33.
ITGA3 forms the alpha3beta1 integrin complex, which is involved in neural migration and corticogenesis in cooperation with the beta-1 subunit.
A functional link between DAB1 phosphorylation and ITGA3 signaling regulates neuronal detachment from radial glial fibers.
Expression of human ITGA3 enhances viral infectivity in Chinese hamster ovary cells.
The protein includes 13 potential N-glycosylation sites, 2 cleavage sites, and 7 N-terminal repeating units typical of integrins.
Recombinant ITGA3 appears as a 150-kDa protein, matching the native form in Western blot analysis.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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