Thermo Fisher Scientific ERN1 Monoclonal Antibody (6G11)
Thermo Fisher Scientific의 ERN1 Monoclonal Antibody (6G11)은 인간 ERN1 단백질을 인식하는 Mouse IgG2a 항체로, Western blot과 ELISA에 적합합니다. 고순도의 친화 크로마토그래피 정제 제품이며, PBS(pH 7.4) 용액에 보존제가 포함되지 않습니다.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1–5 µg/mL |
| ELISA | 0.3 ng/mL |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG2a, kappa |
| Class | Monoclonal |
| Type | Antibody |
| Clone | 6G11 |
| Immunogen | ERN1 (AAC25991, 401 a.a. ~500 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 kDa. |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | See Label |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.4 |
| Contains | No preservative |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
Sequence of this protein is as follows:
EEVINLVDQT SENAPTTVSR DVEEKPAHAP ARPEAPVDSM LKDMATIILS TFLLIGWVAF IITYPLSMHQ QQQLQHQQFQ KELEKIQLLQ QQQQQLPFHP
Target Information
ERN1 (endoplasmic reticulum to nucleus signaling 1) is a serine/threonine kinase and endoribonuclease that acts as a key sensor in the unfolded protein response (UPR) pathway. It transmits ER stress signals to the nucleus by splicing XBP1 mRNA, converting it into a potent transcriptional activator. ERN1 plays an essential role in maintaining cellular homeostasis under stress conditions and is critical for fetal viability.
Usage Notice
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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