Thermo Fisher Scientific PILRA Polyclonal Antibody
Human PILRA 단백질을 인식하는 Rabbit Polyclonal Antibody로, Western blot에 최적화되어 있습니다. N-terminal 합성 펩타이드(aa 51-100)를 면역원으로 사용하며, 고순도 Affinity Chromatography 정제 제품입니다. PBS + sucrose buffer, -20°C 보관 조건.
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Applications
- Western Blot (WB): 0.2–1 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide directed towards the N-terminal of human PILRA (aa 51–100) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.5 mg/mL |
| Purification | Affinity Chromatography |
| Storage Buffer | PBS with 2% sucrose |
| Contains | 0.09% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Wet ice |
| RRID | AB_2576622 |
Product Specific Information
- Peptide sequence: IPFSFYYPWE LATAPDVRIS WRRGHFHRQS FYSTRPPSIH KDYVNRLFLN
- Sequence homology: Human: 100%
Target Information
SHP-1-mediated dephosphorylation of protein tyrosine residues is central to the regulation of several cell signaling pathways. Two types of inhibitory receptor superfamily members are immunoreceptor tyrosine-based inhibitory motif (ITIM)-bearing receptors and their non-ITIM-bearing, activating counterparts. Control of cell signaling via SHP-1 is thought to occur through a balance between PILRα-mediated inhibition and PILRβ-mediated activation. These paired immunoglobulin-like receptor genes are located in a tandem head-to-tail orientation on chromosome 7. This gene encodes the ITIM-bearing member of the receptor pair, functioning in the inhibitory role.
For Research Use Only.
Not for use in diagnostic procedures. Not for resale without express authorization.
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