Thermo Fisher Scientific NOD2 Polyclonal Antibody, MaxPab

Applications

• Western Blot (WB): 1–5 µg/mL

Product Specifications

Product Specific Information

Sequence of this protein is as follows:

MGEEGGSASH DEEERASVLL GHSPGCEMCS QEAFQAQRSQ LVELLVSGSL EGFESVLDWL LSWEVLSWED
YEGFHLLGQP LSHLARRLLD TVWNKGTWAC QKLIAAAQEA QADSQSPKLH GCWDPHSLHP ARDLQSHRPA
IVRRLHSHVE NMLDLAWERG FVSQYECDEI RLPIFTPSQR ARRLLDLATV KANGLAAFLL QHVQELPVPL
ALPLEAATCK KYMAKLRTTV SAQSRFLSTY DGAETLCLED IYTENVLEVW ADVGMAGPPQ KSPATLGLEE
LFSTPGHLND DADTVLVVGE AGSGKSTLLQ RLHLLWAAGQ DFQEFLFVFP FSCRQLQCMA KPLSVRTLLF
EHCCWPDVGQ EDIFQLLLDH PDRVLLTFDG FDEFKFRFTD RERHCSPTDP TSVQTLLFNL LQGNLLKNAR
KVVTSRPAAV SAFLRKYIRT EFNLKGFSEQ GIELYLRKRH HEPGVADRLI RLLQETSALH GLCHLPVFSW
MVSKCHQELL LQEGGSPKTT TDMYLLILQH FLLHATPPDS ASQGLGPSLL RGRLPTLLHL GRLALWGLGM
CCYVFSAQQL QAAQVSPDDI SLGFLVRAKG VVPGSTAPLE FLHITFQCFF AAFYLALSAD VPPALLRHLF
NCGRPGNSPM ARLLPTMCIQ ASEGKDSSVA ALLQKAEPHN LQITAAFLAG LLSREHWGLL AECQTSEKAL
LRRQACARWC LARSLRKHFH SIPPAAPGEA KSVHAMPGFI WLIRSLYEMQ EERLARKAAR GLNVGHLKLT
FCSVGPTECA ALAFVLQHLR RPVALQLDYN SVGDIGVEQL LPCLGVCKAL YLRDNNISDR GICKLIECAL
HCEQLQKLAL FNNKLTDGCA HSMAKLLACR QNFLALRLGN NYITAAGAQV LAEGLRGNTS LQFLGFWGNR
VGDEGAQALA EALGDHQSLR WLSLVGNNIG SVGAQALALM LAKNVMLEEL CLEENHLQDE GVCSLAEGLK
KNSSLKILKL SNNCITYLGA EALLQALERN DTILEVWLRG NTFSLEEVDK LGCRDTRLLL

Target Information

NOD2는 apoptosis 조절 단백질 패밀리에 속하며, caspase recruitment-domains, Apaf-1, NOD1을 포함합니다. NOD2는 두 개의 N-terminal CARD, 하나의 nucleotide-binding domain (NBD), 다수의 C-terminal leucine-rich repeats (LRRs)를 포함합니다. 주로 단핵구(monocytes)에서 발현되며, NF-kappaB 조절, 세포 내 세균성 lipopolysaccharide 수용체 역할, 염증성 장질환(IBD)과 크론병(Crohn’s disease)에 관여합니다.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.