Thermo Fisher Scientific POLK Polyclonal Antibody
Rabbit polyclonal antibody targeting human POLK protein. Unconjugated liquid form with 0.3 mg/mL concentration. Suitable for research use in DNA repair and polymerase studies. Stored at 4°C short term or -20°C long term.
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Thermo Fisher Scientific POLK Polyclonal Antibody
Product Specifications
| 항목 | 내용 |
|---|---|
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant Human POLK |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.3 mg/mL |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2665056 |
Product Specific Information
Immunogen sequence:
AMPGFIAKRLC PQLIIVPPNF DKYRAVSKEV KEILADYDPN FMAMSLDEAY LNITKHLEER QNWPEDKRRY FIKMGSSVEN DNPGKEVNKL SEHERSISPL LFEESPSDVQ PPGDPFQVNF EEQNNPQILQ NS
Highest antigen sequence identity to the following orthologs:
- Mouse: 82%
- Rat: 80%
Target Information
External and internal DNA-damaging agents continually threaten the integrity of genetic material in cells. Although a variety of repair mechanisms exist to remove the resulting lesions, some lesions escape repair and block the replication machinery. Members of the Y family of DNA polymerases, such as POLK, permit the continuity of the replication fork by allowing replication through such DNA lesions. Each Y family polymerase has a unique DNA-damage bypass and fidelity profile. POLK is specialized for the extension step of lesion bypass.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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