Thermo Fisher Scientific Dysferlin Polyclonal Antibody
Rabbit polyclonal antibody recognizing human and mouse Dysferlin protein. Suitable for IHC (Paraffin) applications. Detects endogenous Dysferlin levels. Useful for studying LGMD2B and Miyoshi Myopathy. For research use only.
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Applications and Tested Dilution
- Immunohistochemistry (Paraffin) (IHC (P)): 1:20–1:100
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide of human DYSF |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1.8 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.4, with 40% glycerol |
| Contains | 0.05% sodium azide |
| Storage Conditions | -20°C |
| Shipping Conditions | Wet ice |
| RRID | AB_2636794 |
Product Specific Information
This antibody detects endogenous levels of total Dysferlin protein.
Target Information
Dysferlin is the protein product of the 2p13 gene, which is defective in patients with Limb-Girdle Muscular Dystrophy type 2B (LGMD2B) and Miyoshi Myopathy (MM). Dysferlin is normally localized to the muscle plasma membrane. In patients with LGMD2B and MM, immunoreactivity to Dysferlin is severely reduced or lost depending on the mutation type. This antibody is used for the characterization of LGMD2B and MM.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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