Thermo Fisher Scientific CADM1 Polyclonal Antibody
Western blot과 IHC(P)에서 검증된 CADM1 폴리클로날 항체. 사람과 마우스 반응성. Rabbit IgG로 생산되었으며, 항원 친화 크로마토그래피로 정제됨. 단기 4°C, 장기 -20°C 보관 권장. 연구용 전용 제품.
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- PA524196
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Applications and Tested Dilution
| Application | Tested Dilution | Publications |
|---|---|---|
| Western Blot (WB) | 1:1,000 | View 2 publications |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:50–1:100 | – |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse |
| Published Species | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | KLH conjugated synthetic peptide between 66–94 amino acids from the N-terminal region of human CADM1 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.5 mg/mL |
| Purification | Protein A, Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.4 |
| Contains | 0.09% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2541696 |
Target Information
Mediates homophilic cell-cell adhesion in a Ca²⁺-independent manner and heterophilic adhesion with CADM3 and PVRL3. Acts as a tumor suppressor in non-small-cell lung cancer (NSCLC) cells. Interaction with CRTAM promotes NK cell cytotoxicity and IFN-γ secretion by CD8⁺ cells, contributing to tumor rejection. In mast cells, mediates attachment to and communication with nerves, essential for development and survival. Also acts as a synaptic adhesion molecule involved in neuronal migration, axon growth, and spermatogenesis.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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