Thermo Fisher Scientific FAM120A Polyclonal Antibody
Human FAM120A 단백질을 인식하는 Rabbit Polyclonal Antibody. Western blot, IHC, ICC/IF에 적합. 항원 친화 크로마토그래피로 정제된 액상 제품. 산화 스트레스 관련 신호전달 연구용으로 적합. 연구용으로만 사용.
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Thermo Fisher Scientific FAM120A Polyclonal Antibody
Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 0.04–0.4 µg/mL |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:50–1:200 |
| Immunocytochemistry (ICC/IF) | 0.25–2 µg/mL |
Product Specifications
| Property | Description |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant protein corresponding to Human FAM120A (Product #RP-103233) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.2 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.2, with 40% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term, store at -20°C and avoid freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2641237 |
Product Specific Information
Immunogen sequence:
FYPASAYPRH FGPVPPSQGR GRGFAGVCGF GGPYGETVAT GPYRAFRVAA ASGHCGAFSG SDSSRTSKSQ GGVQPIP
Ortholog Sequence Identity:
- Mouse: 96%
- Rat: 90%
Target Information
FAM120A may participate in mRNA transport in the cytoplasm and act as a critical component of oxidative stress-induced survival signaling. It activates Src family kinases and serves as a scaffolding protein enabling phosphorylation and activation of PI3-kinase. Additionally, it binds RNA and promotes secretion of IGF-II, potentially playing a pivotal role in the progression of scirrhous-type gastric cancer by supporting cancer cell survival under oxidative stress conditions. [UniProt]
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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