Thermo Fisher Scientific ACVR2B Recombinant Rabbit Monoclonal Antibody (7B10)
인간 ACVR2B 단백질을 인식하는 토끼 단클론 항체로, IHC(P) 및 ELISA에 사용 가능. HEK293 세포에서 발현된 재조합 항체이며, 액상 형태로 제공. 친화 크로마토그래피로 정제되었으며, PBS/glycerol 완충액에 보관.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:50–1:200 |
| ELISA | Assay-dependent |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Expression System | HEK293 cells |
| Class | Recombinant Monoclonal |
| Type | Antibody |
| Clone | 7B10 |
| Immunogen | A synthesized peptide derived from human Activin Receptor Type IIB |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.38 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.4, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C or -80°C if preferred |
| Shipping Conditions | Wet ice |
| RRID | AB_3092803 |
Target Information
ACVR2B is a type II member of the TGF-beta family of receptor serine/threonine kinases and is involved in the activin and myostatin signaling pathway. Activins and inhibins are members of the TGF-beta superfamily due to amino acid homology, sharing seven of the nine conserved cysteine residues common to all TGF-beta forms. To date, seven type I and five type II activin receptors have been cloned from mammals, including activin receptor IA, IIA, IB, and IIB. Additionally, two splice variants of activin receptor IIA and five splice variants of activin receptor IIB have been reported.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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