Thermo Fisher Scientific CRYGS Polyclonal Antibody
CRYGS 단백질을 인식하는 Rabbit Polyclonal Antibody로, Western blot에 적합합니다. Human 및 Mouse 시료에 반응하며, 고순도의 affinity chromatography로 정제되었습니다. PBS 기반의 안정한 저장용액으로 장기 보관이 가능합니다.
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Applications
- Western Blot (WB): 1:500–1:2,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Full length fusion protein of human CRYGS |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1.2 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.4, with 40% glycerol |
| Contains | 0.05% sodium azide |
| Storage Conditions | -20°C |
| Shipping Conditions | Wet ice |
| RRID | AB_2692246 |
Product Specific Information
- Predicted to react with Human samples.
Target Information
Crystallins are divided into two main classes: taxon-specific (enzyme) and ubiquitous types. The ubiquitous crystallins are the major structural proteins of the vertebrate eye lens, maintaining transparency and refractive index. Lens fiber cells lose their nuclei during development, so crystallins synthesized early in life are retained, making them highly stable proteins.
Mammalian lens crystallins are categorized into alpha, beta, and gamma families, with beta and gamma forming a superfamily. Gamma-crystallins are monomeric, symmetrical proteins that lack connecting peptides and terminal extensions, and are regulated differently after early development.
The CRYGS gene encodes a gamma-crystallin that is abundant in adult eye lens tissue and has been implicated in cataract formation due to aging or genetic mutations.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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