Thermo Fisher Scientific GSPT1 Monoclonal Antibody (CL5506)
Human GSPT1 단백질을 인식하는 Mouse IgG1 단클론 항체로, eRF3a 단백질 연구에 적합. 비결합형 액상 형태이며, 0.7 mg/mL 농도. 단백질 번역 종료 조절 및 세포 성장 연구용으로 사용 가능.
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Thermo Fisher Scientific GSPT1 Monoclonal Antibody (CL5506)
제품 개요
이 항체는 인간 GSPT1 단백질에 대응하는 합성 펩타이드를 면역원으로 하여 제작된 Mouse IgG1 단클론 항체입니다. eRF3a 단백질 연구 및 번역 종료 조절 메커니즘 분석에 활용됩니다.
제품 사양
| 항목 | 내용 |
|---|---|
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | CL5506 |
| Immunogen | Synthetic peptide corresponding to Human GSPT1 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.7 mg/mL |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2787057 |
Product Specific Information
Immunogen sequence: GAGSGAGGRA APVESSQEE
Target Information
eRF3a (eukaryotic peptide chain release factor subunit 3a), also known as GSPT1 (G1 to S phase transition 1), is a 499 amino acid protein that belongs to the GTP-binding elongation factor family. It regulates cell growth through control of translation termination.
Human eRF3a shares 94% sequence identity with its mouse counterpart, indicating conserved function across species.
The gene encoding eRF3a maps to human chromosome 16, which encodes over 900 genes and comprises nearly 3% of the human genome. Mutation in the GAN gene on chromosome 16 may lead to giant axonal neuropathy, a nervous system disorder characterized by progressive malfunction with growth.
주의사항
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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