Thermo Fisher Scientific GSPT1 Monoclonal Antibody (CL5506)

Thermo Fisher Scientific GSPT1 Monoclonal Antibody (CL5506)

제품 개요

이 항체는 인간 GSPT1 단백질에 대응하는 합성 펩타이드를 면역원으로 하여 제작된 Mouse IgG1 단클론 항체입니다. eRF3a 단백질 연구 및 번역 종료 조절 메커니즘 분석에 활용됩니다.

제품 사양

Product Specific Information

Immunogen sequence: GAGSGAGGRA APVESSQEE

Target Information

eRF3a (eukaryotic peptide chain release factor subunit 3a), also known as GSPT1 (G1 to S phase transition 1), is a 499 amino acid protein that belongs to the GTP-binding elongation factor family. It regulates cell growth through control of translation termination.
Human eRF3a shares 94% sequence identity with its mouse counterpart, indicating conserved function across species.
The gene encoding eRF3a maps to human chromosome 16, which encodes over 900 genes and comprises nearly 3% of the human genome. Mutation in the GAN gene on chromosome 16 may lead to giant axonal neuropathy, a nervous system disorder characterized by progressive malfunction with growth.

주의사항

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.