Thermo Fisher Scientific TG Monoclonal Antibody (OTI8F7), TrueMAB
인간 Thyroglobulin(TG)을 인식하는 마우스 단클론 항체. IHC(P)에서 1:150 희석으로 검증됨. 동결건조 형태로 공급되며, PBS(8% 트레할로스) 버퍼에 용해 가능. 연구용으로만 사용.
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Applications
- Immunohistochemistry (Paraffin) (IHC (P)): Tested dilution 1:150
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI8F7 |
| Immunogen | Human recombinant protein fragment corresponding to amino acids 20–358 of human TG produced in E. coli |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage buffer | PBS, pH 7.3, with 8% trehalose |
| Contains | No preservative |
| Storage conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
For reconstitution, add 100 µL distilled water to achieve a final antibody concentration of approximately 1 mg/mL.
For conjugation experiments, perform an additional desalting step using Zeba Spin Desalting Columns (7K MWCO, 0.5 mL, Product #89882).
Target Information
Human thyroglobulin (hTg) is a high molecular weight glycoprotein (605 kDa) found in thyroid follicular cells. It plays a central role in the uptake, incorporation, and regulated biosynthesis of thyroid hormones T4 and T3.
Autoantibodies against hTg are associated with autoimmune thyroid diseases such as Hashimoto thyroiditis and Graves disease, and are also characteristic of thyroid cancer. Measurement of anti-hTG levels can be useful for monitoring thyroid cancer patients.
For Research Use Only.
Not for use in diagnostic procedures.
Not for resale without express authorization.
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