Thermo Fisher Scientific N-cadherin Monoclonal Antibody (3B9)
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카탈로그 번호 | CAS 번호 | 설명 | 상태 | 단위 | 판매가 | 할인가 | 가격(VAT포함) | 수량 / 장바구니 / 찜 |
333900 | - | Thermo Fisher Scientific 333900 N-cadherin Monoclonal Antibody (3B9) 100 ug pk | 재고문의 | pk | 572,000원 | - | 629,200원 |
다른 상품 둘러보기
Applications
Tested Dilution
Publications
Western Blot (WB)
1:500-1:1,000
View 65 publications 65 publications
Immunohistochemistry (IHC)
-
View 48 publications 48 publications
Immunohistochemistry (Paraffin) (IHC (P))
1-5 µg/mL
View 26 publications 26 publications
Immunohistochemistry (Frozen) (IHC (F))
-
View 8 publications 8 publications
Immunocytochemistry (ICC/IF)
1-3 µg/mL
View 28 publications 28 publications
Flow Cytometry (Flow)
-
View 2 publications 2 publications
Immunoprecipitation (IP)
3-5 µg
View 1 publication 1 publication
Miscellaneous PubMed (Misc)
-
View 18 publications 18 publications
Product Specifications
Species Reactivity
Chicken, Human, Mouse, Pig, Rat
Published species
Avian, Dog, Hamster, Horse, Human, Mouse, Non-human primate, Pig, Rabbit, Rat, Rhesus monkey, Tag, Zebrafish
Host/Isotype
Mouse / IgG1, kappa
Class
Monoclonal
Type
Antibody
Clone
3B9
Immunogen
Recombinant domain corresponding to the intracellular domain of chicken N-Cadherin
Conjugate
Unconjugated Unconjugated Unconjugated
Form
Liquid
Concentration
0.5 mg/mL
Purification
Protein A
Storage buffer
PBS, pH 7.4
Contains
0.1% sodium azide
Storage conditions
-20°C
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
AB_2313779
Product Specific Information
This antibody is specific for N-cadherin and does not cross-react with other cadherin family members including P- and E-cadherins.
For IHC with this antibody use formalin-fixed, paraffin-embedded tissue and heat-induced epitope retrieval.
Target Information
N-cadherin is a 140 kDa protein belonging to a family of transmembrane molecules that mediate calcium-dependent intercellular adhesion. Cadherins are involved in controlling morphogenetic movements during development and regulate cell surface adhesion through homotypic adhesion with the same cadherin species. N-cadherin`s function is dependent on its association with the actin-cytoskeleton and is mediated through interactions between the C-terminal region of N-cadherin and the cytoplasmic catenin proteins. The stability of this association is regulated by phosphorylation and dephosphorylation of beta-catenin. Further, N-cadherin is a calcium dependent cell-cell adhesion glycoprotein comprised of five extracellular cadherin repeats, a transmembrane region and a highly conserved cytoplasmic tail. The protein functions during gastrulation and is required for establishment of left-right asymmetry.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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