Thermo Fisher Scientific Phospho-AS160 (Thr642) Recombinant Rabbit Monoclonal Antibody (10H18L7)

Thermo Fisher Scientific Phospho-AS160 (Thr642) Recombinant Rabbit Monoclonal Antibody (10H18L7)

Applications and Tested Dilution

• Western Blot (WB): 2–3 µg/mL
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Product Specifications

Product Specific Information

• Intact IgG appears on a non-reducing gel as ~150 kDa band and upon reduction generates ~25 kDa light chain and ~50 kDa heavy chain bands.
• Recombinant rabbit monoclonal antibodies are produced using in vitro expression systems developed by cloning specific antibody DNA sequences from immunoreactive rabbits.
• Advantages include:
  • Better specificity and sensitivity
  • Lot-to-lot consistency
  • Animal origin-free formulations
  • Broader immunoreactivity to diverse targets due to larger rabbit immune repertoire

Target Information

AS160 (TBC1D4) is a GTPase-activating protein for RAB2A, RAB8A, RAB10, and RAB14.
Isoform 2 promotes insulin-induced glucose transporter SLC2A4/GLUT4 translocation to the plasma membrane, increasing glucose uptake.
Mutations in this gene are associated with Diabetes mellitus, non-insulin-dependent, type 5 (NIDDM5).

For Research Use Only.
Not for use in diagnostic procedures.
Not for resale without express authorization.