Thermo Fisher Scientific MMRN1 Polyclonal Antibody
MMRN1 단백질을 인식하는 Thermo Fisher Scientific의 폴리클로날 항체로, 인간 시료에 반응하며 Western blot에 적합합니다. 고순도 정제된 Rabbit IgG 형태로 제공되며, 안정적인 PBS buffer에 보관됩니다. 연구용으로만 사용 가능합니다.
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Applications
- Western Blot (WB): Tested dilution 1:1,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | KLH conjugated synthetic peptide between 179–207 amino acids from the N-terminal region of human MMRN1 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.4 mg/mL |
| Purification | Protein A, Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.4 |
| Contains | 0.09% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2634273 |
Target Information
Multimerin-1 (MMRN1), also known as EMILIN-4 or endothelial cell multimerin (ECM), is a 1,228 amino acid secreted protein containing one C1q domain, one EMI domain, and one EGF-like domain. It is synthesized in megakaryocytes and endothelial cells and found in liver, lung, and placenta. Multimerin-1 forms multimeric structures via disulfide linkages and acts as a carrier for platelet factor V, playing a role in its stabilization and storage. It also serves as a ligand for select integrins, contributing to extracellular matrix adhesion. Mutations causing Multimerin-1 deficiency are associated with autosomal dominant bleeding disorders due to platelet factor malfunction. Multiple isoforms exist due to alternative splicing.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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