Thermo Fisher Scientific CABP7 Polyclonal Antibody

Applications

Tested Dilution

Publications

Western Blot (WB)

0.04-0.4 µg/mL

-

Immunohistochemistry (Paraffin) (IHC (P))

1:20-1:50

-

Product Specifications

Species Reactivity

Human

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

Recombinant protein corresponding to Human CABP7. Recombinant protein control fragment (Product #RP-91369). if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:CABP7,uniProtId:Q86V35-1,ncbiNodeId:9606,antigenRange:35-184,antigenLength:215,antigenImageFileName:PA5-53423_CABP7_Q86V35-1_Rabbit.svg,antigenImageFileNamePDP:PA5-53423_CABP7_Q86V35-1_Rabbit_PDP.jpeg,sortOrder:1}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

View immunogen .st0{fill:#FFFFFF;} .st1{fill:#1E8AE7;}

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

0.1 mg/mL

Purification

Antigen affinity chromatography

Storage buffer

PBS, pH 7.2, with 40% glycerol

Contains

0.02% sodium azide

Storage conditions

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Shipping conditions

Wet ice

RRID

AB_2639210

Product Specific Information

Immunogen sequence: LEEIREAFKV FDRDGNGFIS KQELGTAMRS LGYMPNEVEL EVIIQRLDMD GDGQVDFEEF VTLLGPKLST SGIPEKFHGT DFDTVFWKCD MQKLTVDELK RLLYDTFCEH LSMKDIENII MTEEESHLGT AEECPVDVET CSNQQIRQTC

Highest antigen sequence identity to the following orthologs: Mouse - 100%, Rat - 100%.

Target Information

Calcium binding proteins (CaBP) play a crucial role in the calcium-mediated cellular signal transduction pathway in the central nervous system. The CaBP family shares much similarity with CaM I (calmodulin), and it has been shown that CaBP proteins can substitute functionally for, and possibly augment the function of, CaM I. CaBP7 (Calcium-binding protein 7), contains two EF-hand domains for calcium binding and shares 70% homology with CaBP8 and 50% homology with CaM I. It negatively regulates Golgi-to-plasma membrane trafficking by interacting with PI4KB and inhibiting its activity. CaBP7 and 8 possess a targeting mechanism that is unique amongst the CaBPs that may contribute to differential functional Ca2+-sensing by these family members.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.