Thermo Fisher Scientific ADAM8 Polyclonal Antibody
ADAM8 단백질을 인식하는 Thermo Fisher Scientific의 토끼 폴리클로날 항체입니다. Western blot 및 ELISA에 적합하며 인간, 마우스, 랫트 시료에 반응합니다. 액상 형태로 제공되며, 친화 크로마토그래피로 정제되었습니다. 연구용으로만 사용 가능합니다.
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Applications
Western Blot (WB)
- Tested Dilution: 1:500–1:1,000
ELISA
- Tested Dilution: 1 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant fusion protein containing a sequence corresponding to amino acids 17–300 of human ADAM8 (NP_0011003) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 2.336 mg/mL |
| Purification | Affinity Chromatography |
| Storage Buffer | PBS, pH 7.3, with 50% glycerol |
| Contains | 0.09% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Wet ice |
| RRID | AB_2804528 |
Product Specific Information
- Positive Samples: BxPC-3, NIH/3T3
- Cellular Location: Membrane, Single-pass type I membrane protein
Immunogen sequence:
IAPSRPWALM EQYEVVLPWR LPGPRVRRAL PSHLGLHPER VSYVLGATGH NFTLHLRKNR DLLGSGYTET YTAANGSEVT EQPRGQDHCF YQGHVEGYPD SAASLSTCAG LRGFFQVGSD LHLIEPLDEG GEGGRHAVYQ AEHLLQTAGT CGVSDDSLGS LLGPRTAAVF RPRPGDSLPS RETRYVELYV VVDNAEFQML GSEAAVRHRV LEVVNHVDKL YQKLNFRVVL VGLEIWNSQD RFHVSPDPSV TLENLLTWQA RQRTRRHLHD NVQLITGVDF TGTT
Target Information
This gene encodes a member of the ADAM (a disintegrin and metalloprotease domain) family. Members of this family are membrane-anchored proteins structurally related to snake venom disintegrins and are implicated in biological processes involving cell-cell and cell-matrix interactions, including fertilization, muscle development, and neurogenesis.
The encoded protein may be involved in cell adhesion during neurodegeneration and is thought to be a target for allergic respiratory diseases such as asthma.
Alternative splicing results in multiple transcript variants.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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