Thermo Fisher Scientific CHD3 Monoclonal Antibody (5E12)
CHD3 단백질을 인식하는 Thermo Fisher의 Mouse monoclonal 항체. Western blot, IHC(P), ELISA에 사용 가능. Human 시료 반응성. PBS(pH 7.4) 기반 액상형, 보존제 없음. -20°C 보관, 동결/해동 반복 피할 것.
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Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1–5 µg/mL |
| Immunohistochemistry (Paraffin) (IHC (P)) | 3 µg/mL |
| ELISA | 10 µg/mL |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG2a, kappa |
| Class | Monoclonal |
| Type | Antibody |
| Clone | 5E12 |
| Immunogen | CHD3 (NP_001005273, 1654–1741 a.a.) partial recombinant protein with GST tag (GST tag MW: 26 kDa) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | See Label |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.4 |
| Contains | No preservative |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
Sequence of this protein is as follows:
KPLDGQEHRE RPEGETGDLG KREDVKGDRE LRPGPRDEPR SNGRREEKTE KPRFMFNIAD GGFTELHTLW QNEERAAISS GKLNEIWH
Target Information
This gene encodes a member of the CHD family of proteins characterized by chromo domains and SNF2-related helicase/ATPase domains. The protein is part of the Mi-2/NuRD complex involved in chromatin remodeling via histone deacetylation, essential for transcriptional regulation. Autoantibodies against this protein are found in some dermatomyositis patients. Three alternatively spliced transcripts encoding different isoforms have been described.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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