Thermo Fisher Scientific PDX1 Polyclonal Antibody
PDX1 단백질을 인식하는 Thermo Fisher Scientific의 폴리클로날 항체로, 인간 시료에 반응하며 WB, IHC, ICC/IF에 사용 가능. Protein A 및 항원 친화 크로마토그래피로 정제되었으며, 장기 보관 시 -20°C에서 안정적. 인슐린 유전자 발현 연구에 적합.
- 카탈로그번호
- PA511897
- 판매단위
- pk
카탈로그
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Applications
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:1,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:10–1:50 |
| Immunocytochemistry (ICC/IF) | 1:100 |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | KLH conjugated synthetic peptide between 1–30 amino acids from human PDX1 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.25 mg/mL |
| Purification | Protein A, Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.4 |
| Contains | 0.09% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2163100 |
Product Specific Information
This antibody is predicted to react with mouse and rat based on sequence homology.
Target Information
The protein encoded by this gene acts as a transcriptional activator for several genes including insulin, somatostatin, glucokinase, islet amyloid polypeptide, and glucose transporter type 2. It is a nuclear protein involved in early pancreatic development and plays a major role in the glucose-dependent regulation of insulin gene expression. Defects in this gene can cause pancreatic agenesis, leading to early-onset insulin-dependent diabetes mellitus (NIDDM) or maturity-onset diabetes of the young type 4 (MODY4).
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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