Thermo Fisher Scientific GluR4 Polyclonal Antibody
GluR4 단백질을 인식하는 Goat Polyclonal Antibody로, Western blot과 IHC(P)에서 검증됨. 사람과 교차 반응하며, 뇌의 흥분성 신경전달 관련 연구에 적합. 액상 형태로 -20°C 보관, 0.5 mg/mL 농도.
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Applications and Tested Dilution
| Application | Tested Dilution | Publications |
|---|---|---|
| Western Blot (WB) | 1–2 µg/mL | View 2 publications |
| Immunohistochemistry (Paraffin) (IHC (P)) | 5–10 µg/mL | View publications |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Published Species | Human |
| Host / Isotype | Goat / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide sequence (KKLDQREYPGSETP) corresponding to the internal amino acids of GRIA4 (aa 280–294) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.5 mg/mL |
| Purification | Ammonium sulfate precipitation |
| Storage Buffer | TBS, pH 7.3, with 0.5% BSA |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Wet ice |
| RRID | AB_10987221 |
Product Specific Information
- Antibody predicted to react with bovine, mouse, and rat based on sequence homology.
- Tested in Peptide ELISA: antibody detection limit dilution 1:128,000.
Target Information
Glutamate receptors mediate most excitatory neurotransmission in the brain and play an important role in neural plasticity, development, and neurodegeneration.
Ionotropic glutamate receptors are divided into NMDA and kainate/AMPA receptors, both containing glutamate-gated, cation-specific ion channels.
Kainate/AMPA receptors, composed of subunits GluR1–7, are co-localized with NMDA receptors and responsible for fast excitatory neurotransmission by glutamate, whereas NMDA receptors exhibit slower kinetics and higher Ca²⁺ permeability.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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