Thermo Fisher Scientific KIR2DL3 Polyclonal Antibody
인간 KIR2DL3 단백질을 인식하는 Rabbit Polyclonal 항체입니다. IHC, ICC/IF, ELISA 등 다양한 응용에 사용 가능하며, Protein A로 정제된 액상 형태입니다. 안정적인 보관을 위해 -20°C에서 저장합니다.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Immunohistochemistry (Paraffin) (IHC-P) | 1:200 |
| Immunohistochemistry (Frozen) (IHC-F) | 1:100–1:500 |
| Immunocytochemistry (ICC/IF) | 1:100–1:500 |
| ELISA | 1:500–1:1,000 |
Product Specifications
| Item | Description |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | KLH conjugated synthetic peptide derived from human CD158b2/KIR2DL3, amino acids 42–140 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein A |
| Storage Buffer | 0.01M TBS, pH 7.4, with 50% glycerol, 1% BSA |
| Contains | 0.02% ProClin 300 |
| Storage Conditions | -20°C |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
NKAT (NK-associated transcripts) gene products, known as killer immunoglobulin-like receptors (KIRs), downregulate the cytotoxicity of NK cells upon recognition of specific class I MHC molecules on target cells.
This receptor family is characterized by extracellular regions with two to three immunoglobulin-superfamily domains and a cytoplasmic domain containing an antigen receptor activation motif (ARAM).
KIRs and other inhibitory receptors possess a cytoplasmic sequence (I/VxYxxL/V) known as an ITIM (immunoreceptor tyrosine-based inhibitory motif).
The human inhibitory receptor KIR2DL3 (CD158b) specifically recognizes the human MHC class I molecule HLA-Cw3 and related alleles.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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