Thermo Fisher Scientific LIPG Monoclonal Antibody (OTI4C3), TrueMAB
인간 LIPG 단백질을 인식하는 Mouse IgG2b 단일클론 항체로, IHC, ICC/IF, Flow Cytometry, IP에 사용 가능. 친화 크로마토그래피로 정제되었으며, PBS/BSA/glycerol buffer에 보관. HDL 대사 및 지질대사 연구에 적합.
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Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Immunohistochemistry (Paraffin) (IHC-P) | 1:50 |
| Immunocytochemistry (ICC/IF) | 1:100 |
| Flow Cytometry (Flow) | 1:100 |
| Immunoprecipitation (IP) | 2 µg/500 µL |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG2b |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI4C3 |
| Immunogen | Full length human recombinant LIPG protein produced in HEK293T cells |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.76 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS with 1% BSA, 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
LIPG (Lipase G, Endothelial type) is an endothelial lipase and a member of the lipoprotein lipase gene family. It is synthesized by endothelial cells and functions locally to modulate lipoprotein metabolism.
Overexpression of LIPG reduces HDL cholesterol levels, while deficiency elevates HDL levels. LIPG exhibits strong phospholipase activity and plays roles in lipoprotein metabolism and vascular biology.
As a member of the TG lipase family, it possesses a characteristic lid region conferring substrate specificity. LIPG acts as a carboxyl esterase that hydrolyzes HDL, emulsifies triglycerides, aids in dietary fat digestion, and binds heparin.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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