Thermo Fisher Scientific Mist1 Monoclonal Antibody (6E8/A12/C11P1)

Applications

Tested Dilution

Publications

Western Blot (WB)

1:100-1:500

-

Immunohistochemistry (IHC)

-

View 1 publication 1 publication

Immunohistochemistry (Paraffin) (IHC (P))

Assay-dependent

-

Immunohistochemistry (Frozen) (IHC (F))

Assay-dependent

-

Immunocytochemistry (ICC/IF)

-

View 1 publication 1 publication

Product Specifications

Species Reactivity

Human, Mouse

Published species

Human

Host/Isotype

Mouse / IgG1

Class

Monoclonal

Type

Antibody

Clone

6E8/A12/C11P1

Immunogen

Mouse Mist1, C-terminus residues 175-197. if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:Mist1,uniProtId:Q9QYC3-1,ncbiNodeId:10090,antigenRange:175-197,antigenLength:197,antigenImageFileName:MA1-517_Mist1_Q9QYC3-1_House_mouse.svg,antigenImageFileNamePDP:MA1-517_Mist1_Q9QYC3-1_House_mouse_PDP.jpeg,sortOrder:2}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

View immunogen .st0{fill:#FFFFFF;} .st1{fill:#1E8AE7;}

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

1 mg/mL

Purification

Protein A

Storage buffer

PBS with 1mg/mL BSA

Contains

0.05% sodium azide

Storage conditions

-20° C, Avoid Freeze/Thaw Cycles

Shipping conditions

Ambient (domestic); Wet ice (international)

RRID

AB_2259158

Product Specific Information

MA1-517 detects Mist1 from mouse and human samples.

MA1-517 has been successfully used in Western blot, immunohistochemistry procedures. The antibody reactivity in IP and ChIP is weaker than in other applications. By Western blot, MA1-517 detects a ~29 kDa band representing Mist1.

The MA1-517 immunogen is mouse Mist1, C-terminus residues 175-197.

Target Information

Plays a role in controlling the transcriptional activity of MYOD1, ensuring that expanding myoblast populations remain undifferentiated. Repression may occur through muscle-specific E-box occupancy by homodimers. May also negatively regulate bHLH-mediated transcription through an N-terminal repressor domain. Serves as a key regulator of acinar cell function, stability, and identity. Also required for normal organelle localization in exocrine cells and for mitochondrial calcium ion transport. May function as a unique regulator of gene expression in several different embryonic and postnatal cell lineages. Binds to the E-box consensus sequence 5-CANNTG-3.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.