Thermo Fisher Scientific HSP90 beta Polyclonal Antibody, Alexa Fluor 555
HSP90 beta 단백질을 인식하는 Alexa Fluor 555 결합 폴리클로날 항체. 인간, 생쥐, 원숭이, 랫드에 반응하며, 형광 이미징(ICC/IF)에 적합. 항원 친화 크로마토그래피로 정제되었으며, 4°C 암소 보관 권장.
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Applications
Immunocytochemistry (ICC/IF)
- Tested Dilution: 1–10 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Non-human primate, Rat |
| Host/Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide corresponding to residues P(2) EEVHHGEEEVE(13) of mouse HSP84 |
| Conjugate | Alexa Fluor™ 555 |
| Excitation/Emission Max | 553 / 568 nm |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage buffer | PBS, pH 7.4, with 1 mg/mL BSA |
| Contains | 0.05% sodium azide |
| Storage conditions | 4°C, store in dark, DO NOT FREEZE! |
| Shipping conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2662795 |
Product Specific Information
PA3012A555 detects heat shock protein 90 beta (HSP90) from human, monkey, mouse, and rat tissues and cells. This antibody does not detect HSP86.
The immunogen is a synthetic peptide corresponding to residues P(2) EEVHHGEEEVE(13) of mouse HSP84. The N-terminal regions of HSP84 and HSP86 show the largest difference in amino acid sequence.
Target Information
Heat shock proteins (HSP) are expressed in response to various biological stresses, including heat. HSP90 is a 90 kDa protein induced under stress conditions but also abundantly expressed under non-stress conditions.
HSP90 proteins are conserved molecular chaperones involved in signal transduction, protein folding, degradation, and morphologic evolution. They associate with cochaperones and play roles in folding newly synthesized proteins or refolding denatured proteins after stress.
HSP90 interacts with multiple intracellular proteins, including steroid receptors, actin, tubulin, aryl hydrocarbon (Ah) receptor, and various kinases.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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