Thermo Fisher Scientific TNNI2 Monoclonal Antibody (7G2), HRP

Applications

Tested Dilution

Publications

Western Blot (WB)

Assay-dependent

-

ELISA (ELISA)

Assay-dependent

-

Affinity Purification (AP)

Assay-dependent

-

Product Specifications

Species Reactivity

Human

Host/Isotype

Mouse / IgG2b

Class

Monoclonal

Type

Antibody

Clone

7G2

Immunogen

Full length native protein (purified) (Human) if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:TNNI2,uniProtId:P48788-1,ncbiNodeId:9606,antigenRange:1-182,antigenLength:182,antigenImageFileName:MA1-34880_TNNI2_P48788-1_House_mouse.svg,antigenImageFileNamePDP:MA1-34880_TNNI2_P48788-1_House_mouse_PDP.jpeg,sortOrder:1}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

View immunogen .st0{fill:#FFFFFF;} .st1{fill:#1E8AE7;}

Conjugate

HRP HRP HRP

View additional formats

• Unconjugated
• Request custom conjugation

Form

Liquid

Concentration

0.6 mg/mL

Purification

Protein A

Storage buffer

PBS, pH 7.4

Contains

0.05% ProClin 300

Storage conditions

4° C, do not freeze

Shipping conditions

Wet ice

RRID

AB_1961147

Product Specific Information

Cross-reactivity with cardiac TnI is less than 1.5%.

Target Information

This gene encodes a fast-twitch skeletal muscle protein, a member of the troponin I gene family, and a component of the troponin complex including troponin T, troponin C and troponin I subunits. The troponin complex, along with tropomyosin, is responsible for the calcium-dependent regulation of striated muscle contraction. Mouse studies show that this component is also present in vascular smooth muscle and may play a role in regulation of smooth muscle function. In addition to muscle tissues, this protein is found in corneal epithelium, cartilage where it is an inhibitor of angiogenesis to inhibit tumor growth and metastasis, and mammary gland where it functions as a co-activator of estrogen receptor-related receptor alpha. This protein also suppresses tumor growth in human ovarian carcinoma. Mutations in this gene cause myopathy and distal arthrogryposis type 2B. Alternatively spliced transcript variants have been found for this gene.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.