Thermo Fisher Scientific DCAF12 Polyclonal Antibody

Applications and Tested Dilution

• Application: Western Blot (WB)
• Tested Dilution: 0.2–1 µg/mL

Product Specifications

Product Specific Information

• Immunogen sequence: TKSDARHNVS RVPVYAHITH KALKDIPKED TNPDNCKVRA LAFNNKNKEL
• Storage recommendation:
  • Short-term: store at 2–8°C up to 1 week
  • Long-term: store at -20°C in small aliquots to prevent freeze-thaw cycles
• Predicted homology:
  Cow: 100%; Dog: 100%; Guinea Pig: 100%; Horse: 100%; Human: 100%; Mouse: 100%; Rabbit: 100%; Rat: 100%

Target Information

Cancer-testis (CT) antigens are a class of antigens with restricted expression, typically limited to normal testis but aberrantly expressed in various tumors. Their immunogenicity in cancer patients makes them promising targets for tumor immunotherapy.
TCC52, a novel centrosomal protein, is one such CT antigen. It is a WD repeat-containing protein that interacts with the COP9 signalosome, a complex that regulates cullin-RING E3 ligases by hydrolyzing cullin-Nedd8 conjugates. The normal biological function of this protein remains unknown.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.